| Design | International RCT, n=2,003 (PREVENT) |
| Published | 2019 (NEJM) |
| Result | Adding intermittent pneumatic compression to pharmacological thromboprophylaxis did not reduce proximal DVT rates compared to pharmacological prophylaxis alone (3.9% vs 4.2%). |
| Practice impact | Mechanical compression devices are no longer routinely recommended in ICU patients already receiving chemical thromboprophylaxis. |
Source: The Bottom Line